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adenylate kinase may end up in conversion of ADP into ATP and AMP and thereby confound interpretation with the ADP/ATP specificity experiments. Resolving the conundrum of how some twin-specificity archaeal ligases may make use of ATP and NAD+ will depend upon capturing crystal buildings of these enzymes with Each and every nucleotide certain.
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The movement entails a rigid human body rotation concerning the hinge section connecting the NTase and OB domains (indicated via the arrow
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